Fmoc-His(Boc)-OH

Name: Fmoc-His(Boc)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 81379-52-4
Cat. No. CS-0067108
Purity≥95%
MDL No.MFCD00151928

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 81379-52-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Fmoc-His(Boc)-OH is a protected histidine derivative designed for solid-phase peptide synthesis. The Fmoc group enables orthogonal protection, while the Boc moiety stabilizes the imidazole side chain. This combination ensures high fidelity during coupling steps and simplifies deprotection workflows. The molecule exhibits excellent solubility in common organic solvents and maintains stability under standard bench conditions.

Application

Fmoc-His(Boc)-OH serves as a key building block in solid-phase peptide synthesis, offering orthogonal protection of both the Nα-amino and imidazole side-chain functionalities. The Fmoc group enables base-labile removal under mild conditions, while the Boc-protected imidazole ensures stability during coupling steps. This derivative facilitates efficient incorporation of histidine residues with high fidelity, supports clean deprotection sequences, and enhances purification ease due to improved solubility and reduced aggregation.

General Information

CAS No. 81379-52-4
Cat. No. CS-0067108
Purity ≥95%
MDL No. MFCD00151928
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₆H₂₇N₃O₆
Molecular Weight 477.51
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CN(C(OC(C)(C)C)=O)C=N1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Computational Chemistry Data

TPSA 119.75
LogP 4.2007
H_Acceptors 7
H_Donors 2
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Histidine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

Key Words

Fmoc-His(Boc)-OH sigmaFmoc-His(Boc)-OH manufacturerFmoc-His(Boc)-OH priceFmoc-His(Boc)-OH structureFmoc-His(Boc)-OH SDSbuy Fmoc-His(Boc)-OHFmoc-His(Boc)-OH supplierFmoc-His(Boc)-OH usesFmoc-His(Boc)-OH molecular weightprice of Fmoc-His(Boc)-OHFmoc-His(Boc)-OH chemical name formula of Fmoc-His(Boc)-OH

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Fmoc-His(Boc)-OH

CAS No. 81379-52-4

Recommended Products