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CS-W001157 4
Total: USD 88.00

4-(bis(4-Iodophenyl)amino)benzaldehyde

  • CAS No. 808758-81-8

  • Cat. No. CS-0136570
  • Purity≥96%
  • MDL No.MFCD20259247

*For research and further manufacturing use only, not for direct human use.

4-(bis(4-Iodophenyl)amino)benzaldehyde|CS-0136570

Structure of 808758-81-8

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General Information

  • CAS No. 808758-81-8
  • Cat. No. CS-0136570
  • Purity ≥96%
  • MDL No. MFCD20259247
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₃I₂NO
  • Molecular Weight 525.12
  • Synonym(s) 4-[Bis(4-iodophenyl)amino]benzaldehyde
  • SMILES O=CC1=CC=C(N(C2=CC=C(I)C=C2)C3=CC=C(I)C=C3)C=C1

Description

4-(bis(4-Iodophenyl)amino)benzaldehyde features a central benzaldehyde core flanked by two 4-iodophenyl groups attached via amino linkages, delivering high electron density and enhanced stability. This configuration supports efficient coupling in palladium-catalyzed cross-coupling reactions, enabling rapid access to complex aryl architectures. The molecule exhibits robust performance under standard reaction conditions with minimal decomposition.

Application

4-(bis(4-Iodophenyl)amino)benzaldehyde serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds in pharmaceutical and materials chemistry. The aldehyde functionality provides a handle for further derivatization, while the two iodophenyl groups offer high reactivity in Suzuki-Miyaura and Buchwald-Hartwig couplings. Bench-stable and amenable to purification by flash chromatography, it functions reliably in multi-step syntheses requiring orthogonal functional group handling.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   6.1781
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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