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Structure of 80466-78-0
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3,5-Dimethyl-1H-pyrazole-4-sulfonyl chloride features a sulfonyl chloride group flanked by electron-donating methyl substituents, enhancing reactivity while maintaining bench-stable handling. This scaffold integrates readily into pharmaceutical intermediates and bioactive molecule frameworks via efficient acylation or coupling reactions under standard conditions.
3,5-Dimethyl-1H-pyrazole-4-sulfonyl chloride serves as a versatile sulfonyl chloride building block for the synthesis of pyrazole-based sulfonamides and sulfonate esters. Its electron-donating methyl groups enhance reactivity while maintaining bench stability, enabling efficient coupling with amines and alcohols under mild conditions. The compound exhibits excellent functional group tolerance and facilitates purification via crystallization or chromatography, making it ideal for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: