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Structure of 80194-69-0
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5-(Trifluoromethyl)-2-pyridinecarboxylic acid features a strongly electron-deficient pyridine core augmented by a trifluoromethyl group, enhancing its utility in medicinal chemistry and catalysis. This bench-stable carboxylic acid integrates readily into diverse molecular architectures via standard coupling protocols.
5-(Trifluoromethyl)-2-pyridinecarboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates direct derivatization via amide, ester, or acyl chloride formation. The molecule exhibits excellent bench stability and compatibility with common purification methods, making it ideal for scalable synthesis and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: