H-D-Phe(2-Cl)-OH

Name: H-D-Phe(2-Cl)-OH
Brand: ChemScene
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CAS No. 80126-50-7
Cat. No. CS-W013202
Molecule weight199.63
Purity≥98%
MDL No.MFCD00077920

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 80126-50-7
Cat. No. CS-W013202
Purity ≥98%
MDL No. MFCD00077920
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀ClNO₂
Molecular Weight 199.63
Synonym(s) None
SMILES N[C@H](CC1=CC=CC=C1Cl)C(O)=O

Description

H-D-Phe(2-Cl)-OH is a bench-stable, moisture-tolerant D-amino acid derivative featuring a para-chlorinated phenyl ring. This sterically hindered analog integrates seamlessly into peptide sequences, enhancing metabolic stability while maintaining high affinity for target receptors in bioactive peptide design.

Application

H-D-Phe(2-Cl)-OH serves as a valuable building block in peptide synthesis, offering enhanced metabolic stability and altered electronic properties due to the 2-chloro substitution on the phenyl ring. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient incorporation into bioactive peptides, particularly those targeting neuroendocrine systems or G-protein-coupled receptors.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 63.32
LogP 1.2944
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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H-D-Phe(2-Cl)-OH

CAS No. 80126-50-7

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