2-Chloroethyl 4-methylbenzenesulfonate

Name: 2-Chloroethyl 4-methylbenzenesulfonate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 80-41-1
Cat. No. CS-0130585
Molecule weight234.70
Purity≥97%
MDL No.MFCD00000970

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloroethyl 4-methylbenzenesulfonate|CS-0130585

Structure of 80-41-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 80-41-1
Cat. No. CS-0130585
Purity ≥97%
MDL No. MFCD00000970
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₁ClO₃S
Molecular Weight 234.70
Synonym(s) p-Toluenesulphonic acid 2-chloroethyl ester
SMILES CC1=CC=C(S(=O)(OCCCl)=O)C=C1

Application

2-Chloroethyl 4-methylbenzenesulfonate serves as a reliable alkylating agent for nucleophilic substitution reactions, enabling efficient introduction of the 2-chloroethyl group under mild conditions. Its bench-stable nature and compatibility with diverse nucleophiles—such as amines, thiols, and carboxylates—facilitate straightforward functionalization in synthetic workflows. The tosylate moiety provides excellent leaving group ability, while the methyl-substituted aromatic ring enhances stability and ease of purification. This reagent is particularly valuable in constructing bioactive scaffolds and modifying peptides or small molecules where selective alkylation is required.

Synthesis

Route1
- 98-59-9
- 107-07-3
- ~97%
- In-stock
  
  80-41-1
References
- CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2009/52148 A1, 2009 ; Location in patent: Page/Page column 29 ;
Route2
- 54509-73-8
- ~43%
- In-stock
  
  80-41-1
- 107-06-2
References
- Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 205 - 213 Zhurnal Organicheskoi Khimii, , vol. 20, # 2 p. 233 - 242
Route3
- 107-04-0
- 80-48-8
- ~67%
- In-stock
  
  80-41-1
- 19263-21-9
References
- Journal of Organic Chemistry, , vol. 53, # 24 p. 5783 - 5785

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.37
LogP 1.93912
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 4

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Chloroethyl 4-methylbenzenesulfonate sigma2-Chloroethyl 4-methylbenzenesulfonate manufacturer2-Chloroethyl 4-methylbenzenesulfonate price2-Chloroethyl 4-methylbenzenesulfonate structure2-Chloroethyl 4-methylbenzenesulfonate SDSbuy 2-Chloroethyl 4-methylbenzenesulfonate2-Chloroethyl 4-methylbenzenesulfonate supplier2-Chloroethyl 4-methylbenzenesulfonate uses2-Chloroethyl 4-methylbenzenesulfonate molecular weightprice of 2-Chloroethyl 4-methylbenzenesulfonate2-Chloroethyl 4-methylbenzenesulfonate chemical name formula of 2-Chloroethyl 4-methylbenzenesulfonate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloroethyl 4-methylbenzenesulfonate

CAS No. 80-41-1

Recommended Products

General Information

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words