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(S)-Methyl 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

  • CAS No. 79815-18-2

  • Cat. No. CS-0197436
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-Methyl 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate|CS-0197436

Structure of 79815-18-2

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General Information

  • CAS No. 79815-18-2
  • Cat. No. CS-0197436
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₄N₂O₂
  • Molecular Weight 230.26
  • Synonym(s) H-Tpi-ome hcl
  • SMILES COC(=O)[C@@H]1CC2=C(CN1)NC3=CC=CC=C23

Description

This chiral ester features a rigid, electron-rich tetrahydropyridoindole scaffold ideal for asymmetric synthesis. The (S)-configured methyl ester group enables stereocontrolled derivatization in medicinal chemistry campaigns. Bench-stable and readily soluble in common organic solvents, it serves as a high-fidelity building block for complex heterocyclic systems.

Application

(S)-Methyl 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate serves as a versatile chiral building block for the synthesis of complex indole-based scaffolds. Its well-defined stereochemistry and functionalized pyridine-indole core enable reliable transformations in medicinal chemistry workflows. The ester group facilitates selective derivatization, while the tetrahydro-pyridoindole framework exhibits robust bench stability and compatibility with standard coupling and reduction protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   54.12
  • LogP   1.3552
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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