(R)-(1-ethylpyrrolidin-2-yl)methanol

Name: (R)-(1-ethylpyrrolidin-2-yl)methanol
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CAS No. 79802-13-4
Cat. No. CS-0490845
Molecule weight129.20
Purity≥95%
MDL No.None

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(R)-(1-ethylpyrrolidin-2-yl)methanol|CS-0490845

Structure of 79802-13-4

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General Information

CAS No. 79802-13-4
Cat. No. CS-0490845
Purity ≥95%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₅NO
Molecular Weight 129.20
Synonym(s) [(2R)-1-ethylpyrrolidin-2-yl]methanol
SMILES CCN1[C@@H](CO)CCC1

Description

(R)-(1-ethylpyrrolidin-2-yl)methanol is a chiral building block featuring a stereodefined pyrrolidine ring and a primary alcohol group. This configuration enhances its utility in asymmetric synthesis, particularly for pharmaceutical intermediates requiring precise stereocontrol. The molecule exhibits favorable solubility and stability under standard bench conditions, enabling seamless integration into multi-step synthetic sequences.

Application

(R)-(1-Ethylpyrrolidin-2-yl)methanol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its well-defined stereochemistry and bench-stable nature facilitate reliable incorporation into target molecules. The molecule reacts efficiently with electrophiles and participates in standard coupling and functionalization protocols, offering predictable reactivity for scaffold diversification.

Safety Information

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Computational Chemistry Data

TPSA 23.47
LogP 0.463
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-(1-ethylpyrrolidin-2-yl)methanol

CAS No. 79802-13-4

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