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CS-W001157 4
Total: USD 88.00

4-((tert-Butoxycarbonyl)amino)-2-methylbutanoic acid

  • CAS No. 79799-26-1

  • Cat. No. CS-0197435
  • Molecule weight217.26
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-((tert-Butoxycarbonyl)amino)-2-methylbutanoic acid|CS-0197435

Structure of 79799-26-1

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General Information

  • CAS No. 79799-26-1
  • Cat. No. CS-0197435
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₄
  • Molecular Weight 217.26
  • Synonym(s) 2-Methyl-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid
  • SMILES CC(C(O)=O)CCNC(OC(C)(C)C)=O

Description

This tert-butyl ester derivative features a protected amino group flanked by a methyl-substituted aliphatic chain, enabling stable incorporation into peptide synthesis workflows. The Boc moiety ensures orthogonal handling under standard deprotection conditions, facilitating sequential coupling in complex molecular architectures.

Application

4-((tert-Butoxycarbonyl)amino)-2-methylbutanoic acid serves as a versatile building block for peptide synthesis and medicinal chemistry applications. The Boc-protected amine enables orthogonal functional group manipulation, while the branched aliphatic side chain provides steric differentiation. This compound exhibits excellent bench stability, facilitates straightforward purification via standard chromatographic methods, and participates reliably in standard coupling reactions with minimal epimerization risk.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.6219
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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