Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-6-fluorobenzonitrile

  • CAS No. 79544-27-7

  • Cat. No. CS-W003346
  • Purity≥98%
  • MDL No.MFCD06797753

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-fluorobenzonitrile|CS-W003346

Structure of 79544-27-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 79544-27-7
  • Cat. No. CS-W003346
  • Purity ≥98%
  • MDL No. MFCD06797753
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃BrFN
  • Molecular Weight 200.01
  • Synonym(s) 6-BROMO-2-FLUOROBENZONITRILE
  • SMILES N#Cc1c(F)cccc1Br

Description

2-Bromo-6-fluorobenzonitrile features a strategically positioned nitrile group flanked by bromo and fluoro substituents, enabling direct functionalization in cross-coupling reactions. This electron-deficient aromatic scaffold delivers high reactivity under standard conditions, integrating seamlessly into complex molecular architectures.

Application

2-Bromo-6-fluorobenzonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The nitrile group provides a handle for downstream functionalization, while the meta-fluoro and ortho-bromo substituents offer predictable regioselectivity in electrophilic substitution and Suzuki-Miyaura coupling. Its bench stability and compatibility with standard purification methods make it well-suited for multi-step synthesis.

Synthesis

  • Route1

    References

    • MERCK SHARP and DOHME LIMITED Patent: WO2003/99816 A1, 2003 ; Location in patent: Page 58 ; WO 03/099816 A1
  • Route2

    References

    • Journal of Heterocyclic Chemistry, , vol. 25, p. 1173 - 1177

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   23.79
  • LogP   2.45988
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-6-fluorobenzonitrile sigma2-Bromo-6-fluorobenzonitrile manufacturer2-Bromo-6-fluorobenzonitrile price2-Bromo-6-fluorobenzonitrile structure2-Bromo-6-fluorobenzonitrile SDSbuy 2-Bromo-6-fluorobenzonitrile2-Bromo-6-fluorobenzonitrile supplier2-Bromo-6-fluorobenzonitrile uses2-Bromo-6-fluorobenzonitrile molecular weightprice of 2-Bromo-6-fluorobenzonitrile2-Bromo-6-fluorobenzonitrile chemical name formula of 2-Bromo-6-fluorobenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label