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Structure of 79173-62-9
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3-Methyl-1H-indazol-6-amine features a fused bicyclic indazole core with a methyl group at the 3-position and a primary amine at the 6-position. This configuration supports hydrogen bonding and π-stacking interactions, enhancing binding affinity in kinase inhibition studies. The compound exhibits bench-stable behavior under standard conditions and integrates readily into medicinal chemistry campaigns targeting ATP-binding sites.
3-Methyl-1H-indazol-6-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling reactions. Its ortho-amino functionality facilitates palladium-catalyzed cross-couplings and electrophilic substitutions, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it suitable for iterative synthetic approaches in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: