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Structure of 78871-05-3
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Bis(2-naphthyl)phosphine oxide features a rigid, electron-rich phosphine oxide core that enhances ligand stability and coordination versatility. This sterically encumbered structure promotes selective metal binding in catalytic systems, particularly in palladium-catalyzed cross-coupling reactions. The molecule exhibits robust bench stability and tolerates air and moisture during handling.
Bis(2-naphthyl)phosphine oxide serves as a stable, bench-friendly ligand in transition metal catalysis, particularly in palladium- and nickel-catalyzed cross-coupling reactions. Its electron-donating character and steric profile enhance catalyst activity and selectivity in C–C and C–heteroatom bond formations. The molecule exhibits excellent functional group tolerance and facilitates efficient purification due to its low volatility and thermal stability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: