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Structure of 786616-54-4
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3-Amino-5-fluorobenzoic acid features a strategically positioned amino group flanked by fluorine and carboxylic acid functionalities, enabling precise tuning of electronic properties and solubility. This combination supports direct integration into pharmaceutical scaffolds and functional materials under standard conditions.
3-Amino-5-fluorobenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via standard amide coupling, Suzuki-Miyaura, and Buchwald-Hartwig reactions. Its ortho-amino and meta-fluoro functionalities offer complementary reactivity for sequential functionalization, while the carboxylic acid group facilitates direct derivatization or salt formation. Bench-stable and readily purified by recrystallization, it supports scalable synthesis of API intermediates and heterocyclic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: