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Structure of 785777-88-0
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5-Bromo-4-(trifluoromethyl)pyrimidine is a halogenated pyrimidine scaffold featuring a trifluoromethyl group at the 4-position and a bromine atom at the 5-position. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling efficient coupling reactions for the synthesis of bioactive compounds. The trifluoromethyl moiety enhances metabolic stability and lipophilicity, while the bromine facilitates downstream functionalization via cross-coupling methodologies.
5-Bromo-4-(trifluoromethyl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its electrophilic bromine and electron-withdrawing trifluoromethyl group. The molecule exhibits excellent bench stability, facilitates straightforward purification, and supports the construction of complex heterocyclic scaffolds common in pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: