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Structure of 78449-75-9
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This acetonitrile derivative features a hexahydro-1H-pyrrolizin-7a-yl group that imparts enhanced solubility and metabolic stability. The nitrile moiety enables direct functionalization in synthetic transformations, while the saturated heterocyclic core provides rigidity and favorable pharmacokinetic properties. Ideal for medicinal chemistry campaigns requiring stable, tunable scaffolds.
2-(Hexahydro-1H-pyrrolizin-7a-yl)acetonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of nitrogen-containing heterocyclic scaffolds. Its acetonitrile group facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions, while the saturated pyrrolizidine core provides structural rigidity and favorable pharmacokinetic properties. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: