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CS-W001157 4
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(Hexahydro-1H-pyrrolizin-7a-yl)methanol

  • CAS No. 78449-72-6

  • Cat. No. CS-0081726
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(Hexahydro-1H-pyrrolizin-7a-yl)methanol|CS-0081726

Structure of 78449-72-6

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General Information

  • CAS No. 78449-72-6
  • Cat. No. CS-0081726
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO
  • Molecular Weight 141.21
  • Synonym(s) None
  • SMILES OCC12CCCN1CCC2

Description

(Hexahydro-1H-pyrrolizin-7a-yl)methanol features a saturated pyrrolizidine core with a terminal hydroxymethyl group, offering a rigid, nitrogen-rich scaffold ideal for medicinal chemistry. This bench-stable, moisture-tolerant compound integrates readily into molecular architectures requiring defined stereochemistry and enhanced solubility.

Application

(Hexahydro-1H-pyrrolizin-7a-yl)methanol serves as a versatile nitrogen-containing building block in medicinal chemistry, enabling the construction of saturated heterocyclic scaffolds. Its primary alcohol functionality facilitates straightforward derivatization via esterification, etherification, or oxidation to the aldehyde. The molecule exhibits good bench stability and functional group tolerance, making it suitable for multi-step synthesis workflows. It functions as a key intermediate in the development of bioactive compounds, particularly those requiring constrained pyrrolizidine frameworks with defined stereochemistry.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   0.6071
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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