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Structure of 78443-72-8
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2,4-Dichloro-6-hydroxybenzaldehyde features a hydroxyl group flanked by two chlorine substituents on the aromatic ring, enabling direct participation in hydrogen bonding and enhancing solubility in polar solvents. This electron-deficient aldehyde integrates readily into synthesis pathways requiring orthogonal functionalization, particularly in pharmaceutical intermediates and fluorescent probe development.
2,4-Dichloro-6-hydroxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted heterocycles and functionalized aromatic scaffolds. Its ortho-chlorine substituents facilitate electrophilic substitution, while the aldehyde and phenolic hydroxyl groups offer orthogonal reactivity for coupling, derivatization, and protection strategies. The compound exhibits good bench stability and is compatible with standard purification methods, supporting reliable use in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: