Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Isopropylpyridin-2-amine

  • CAS No. 78177-12-5

  • Cat. No. CS-W006128
  • Purity≥98%
  • MDL No.MFCD09743891

*For research and further manufacturing use only, not for direct human use.

6-Isopropylpyridin-2-amine|CS-W006128

Structure of 78177-12-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 78177-12-5
  • Cat. No. CS-W006128
  • Purity ≥98%
  • MDL No. MFCD09743891
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight None
  • Synonym(s) 6-(1-METHYLETHYL)-2-PYRIDINAMINE
  • SMILES NC1=NC(C(C)C)=CC=C1

Description

6-Isopropylpyridin-2-amine features a sterically hindered isopropyl group at the 6-position, enhancing its stability and solubility in organic media. The pyridin-2-amine core provides a strong nitrogen donor site, enabling efficient coordination in catalytic systems. This compound serves as a robust ligand in transition metal catalysis and functionalizes diverse synthetic intermediates.

Application

6-Isopropylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and direct functionalization. Its ortho-amino group facilitates efficient metal coordination and cyclization reactions, while the isopropyl substituent enhances lipophilicity and metabolic stability. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows, simplifying purification and scale-up.

Synthesis

  • Route1
    • In-stock
      2-Amino-6-bromopyridine|CS-D1448
      19798-81-3
    • null|null
      625-81-0
    • ~%
    • In-stock
      6-Isopropylpyridin-2-amine|CS-W006128
      78177-12-5

    References

    • US2006/74237 A1, ; Page/Page column 17 ;
  • Route2
    • null|null
      115526-98-2
    • ~48%
    • In-stock
      6-Isopropylpyridin-2-amine|CS-W006128
      78177-12-5

    References

    • Pereira, David E.; Clauson, Gary L.; Leonard, Nelson J. Tetrahedron, 1987 , vol. 43, # 21 p. 4931 - 4946
  • Route3

    References

    • Gaillard, Sylvain; Elmkaddem, Mohammed Kamal; Fischmeister, Cedric; Thomas, Christophe M.; Renaud, Jean-Luc Tetrahedron Letters, 2008 , vol. 49, # 21 p. 3471 - 3474

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H301-H310-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.7872
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Isopropylpyridin-2-amine sigma6-Isopropylpyridin-2-amine manufacturer6-Isopropylpyridin-2-amine price6-Isopropylpyridin-2-amine structure6-Isopropylpyridin-2-amine SDSbuy 6-Isopropylpyridin-2-amine6-Isopropylpyridin-2-amine supplier6-Isopropylpyridin-2-amine uses6-Isopropylpyridin-2-amine molecular weightprice of 6-Isopropylpyridin-2-amine6-Isopropylpyridin-2-amine chemical name formula of 6-Isopropylpyridin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label