Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Methylthiophene-3-carboxylic acid

  • CAS No. 78071-30-4

  • Cat. No. CS-W019951
  • Purity≥97%
  • MDL No.MFCD02257717

*For research and further manufacturing use only, not for direct human use.

4-Methylthiophene-3-carboxylic acid|CS-W019951

Structure of 78071-30-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 78071-30-4
  • Cat. No. CS-W019951
  • Purity ≥97%
  • MDL No. MFCD02257717
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆O₂S
  • Molecular Weight 142.18
  • Synonym(s) None
  • SMILES O=C(C1=CSC=C1C)O

Description

4-Methylthiophene-3-carboxylic acid features a thiophene core functionalized with a methyl group at the 4-position and a carboxylic acid at the 3-position, offering a distinct electron-rich heterocyclic scaffold. This structure enables direct integration into conjugated systems and facilitates coupling reactions in synthetic methodologies requiring polar, sulfur-containing building blocks.

Application

4-Methylthiophene-3-carboxylic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its thiophene core provides robust stability and π-conjugation, while the carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation. The methyl group at the 4-position offers a site for selective functionalization, enhancing synthetic flexibility in medicinal chemistry campaigns. This compound exhibits good bench stability and facilitates efficient purification, making it well-suited for scale-up applications in API development.

Synthesis

  • Route1

    References

    • US5420333 A1, ;
  • Route2
    • 3-Iodo-4-methylthiophene|CS-0191818
      16494-41-0
    • ~%
    • In-stock
      4-Methylthiophene-3-carboxylic acid|CS-W019951
      78071-30-4

    References

    • Justus Liebigs Annalen der Chemie, , vol. 532, p. 236,248

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.75472
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Methylthiophene-3-carboxylic acid sigma4-Methylthiophene-3-carboxylic acid manufacturer4-Methylthiophene-3-carboxylic acid price4-Methylthiophene-3-carboxylic acid structure4-Methylthiophene-3-carboxylic acid SDSbuy 4-Methylthiophene-3-carboxylic acid4-Methylthiophene-3-carboxylic acid supplier4-Methylthiophene-3-carboxylic acid uses4-Methylthiophene-3-carboxylic acid molecular weightprice of 4-Methylthiophene-3-carboxylic acid4-Methylthiophene-3-carboxylic acid chemical name formula of 4-Methylthiophene-3-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label