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CS-W001157 4
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Tetraethyl orthocarbonate

  • CAS No. 78-09-1

  • Cat. No. CS-0031801
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tetraethyl orthocarbonate|CS-0031801

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General Information

  • CAS No. 78-09-1
  • Cat. No. CS-0031801
  • Purity ≥97%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₀O₄
  • Molecular Weight 192.25
  • Synonym(s) Tetraethylorthocarbonate
  • SMILES CCOC(OCC)(OCC)OCC

Description

Tetraethyl orthocarbonate was used in the synthesis of 2,7-dimethylene-1,4,6,9-tetraoxaspiro[4,4]nonane. It was used in the synthesis of crosslinked poly(orthocarbonate)s used as organic solvent absorbent.

Application

Tetraethyl orthocarbonate serves as a reliable source of ethoxy groups in synthetic transformations, enabling efficient esterification and carbonyl protection under mild conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward purification and scalability. Widely employed in the construction of heterocyclic scaffolds and as a reagent in nucleophilic substitution reactions, it functions as a versatile building block in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 3272
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

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Computational Chemistry Data

  • TPSA   36.92
  • LogP   1.7437
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   8

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