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CS-W001157 4
Total: USD 88.00

5-(Aminomethyl)-N-methylpyridin-2-amine

  • CAS No. 779324-37-7

  • Cat. No. CS-0357294
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(Aminomethyl)-N-methylpyridin-2-amine|CS-0357294

Structure of 779324-37-7

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General Information

  • CAS No. 779324-37-7
  • Cat. No. CS-0357294
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁N₃
  • Molecular Weight 137.18
  • Synonym(s) None
  • SMILES NCC1=CC=C(NC)N=C1

Description

This pyridine derivative features a strategically positioned aminomethyl group and N-methyl substitution, enabling precise coordination in catalytic systems. The electron-rich aromatic core enhances reactivity in transition-metal-mediated transformations, while the methylated nitrogen improves solubility and metabolic stability. Designed for efficient integration into ligand architectures and bioconjugation workflows under standard conditions.

Application

5-(Aminomethyl)-N-methylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of pyridine-based pharmacophores. Its ortho-amino and methylated nitrogen functionalities provide enhanced solubility and tunable basicity, facilitating downstream derivatization via amide coupling, alkylation, or reductive amination. The molecule exhibits excellent bench stability and compatibility with common protecting group strategies, supporting efficient synthesis of targeted heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   50.94
  • LogP   0.582
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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