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Structure of 77903-28-7
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5-Methoxy-4-methylpyridin-3-amine features a pyridine core functionalized with a methoxy group at C5 and a methyl substituent at C4, delivering enhanced electron density at the 3-amine site. This configuration supports efficient coupling in cross-coupling reactions and improves solubility in polar organic media. The compound exhibits bench-stable behavior under standard conditions, facilitating use in synthetic workflows requiring reliable nitrogen incorporation.
5-Methoxy-4-methylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyridine scaffolds. Its ortho-substituted amine and methoxy groups provide favorable electronic modulation and steric profile for cross-coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: