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Structure of 77811-44-0
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4-Bromo-2-methyl-6-nitroaniline features a bromine atom at the para position relative to the amino group, paired with a methyl substituent and a strongly electron-withdrawing nitro group. This combination imparts enhanced reactivity in cross-coupling processes and facilitates selective functionalization. The molecule exhibits robust stability under standard bench conditions and integrates readily into advanced synthetic sequences for pharmaceutical intermediates and specialty dyes.
4-Bromo-2-methyl-6-nitroaniline serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient construction of substituted heterocycles via palladium-catalyzed coupling reactions. Its ortho-directing nitro group and bromine handle facilitate sequential functionalization, while the methyl substituent enhances metabolic stability in downstream scaffolds. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for iterative synthetic workflows in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: