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CS-W001157 4
Total: USD 88.00

3-(1H-1,2,4-Triazol-1-yl)piperidine

  • CAS No. 774511-83-0

  • Cat. No. CS-0036668
  • Purity98+%
  • MDL No.MFCD14632032

*For research and further manufacturing use only, not for direct human use.

3-(1H-1,2,4-Triazol-1-yl)piperidine|CS-0036668

Structure of 774511-83-0

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General Information

  • CAS No. 774511-83-0
  • Cat. No. CS-0036668
  • Purity 98+%
  • MDL No. MFCD14632032
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂N₄
  • Molecular Weight 152.20
  • Synonym(s) Piperidine, 3-(1H-1,2,4-triazol-1-yl)- (9CI)
  • SMILES C1CC(CNC1)N2C=NC=N2

Description

3-(1H-1,2,4-Triazol-1-yl)piperidine is a nitrogen-rich heterocyclic scaffold featuring a triazole moiety linked to a piperidine ring. This combination imparts enhanced solubility and metabolic stability, enabling efficient integration into bioactive molecules. The compound serves as a key building block in medicinal chemistry for designing kinase inhibitors and CNS-targeted therapeutics.

Application

3-(1H-1,2,4-Triazol-1-yl)piperidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through established coupling and functionalization protocols. The triazolylpiperidine moiety exhibits favorable metabolic stability and hydrogen-bonding capacity, enhancing target affinity in drug discovery. Its bench-stable nature and compatibility with standard synthetic transformations facilitate efficient synthesis of complex molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   42.74
  • LogP   0.2026
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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