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CS-W001157 4
Total: USD 88.00

1-Methyl-4-phenylpiperidine

  • CAS No. 774-52-7

  • Cat. No. CS-W001643
  • Purity≥98%
  • MDL No.MFCD00460869

*For research and further manufacturing use only, not for direct human use.

1-Methyl-4-phenylpiperidine|CS-W001643

Structure of 774-52-7

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General Information

  • CAS No. 774-52-7
  • Cat. No. CS-W001643
  • Purity ≥98%
  • MDL No. MFCD00460869
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇N
  • Molecular Weight 175.27
  • Synonym(s) Piperidine,1-methyl-4-phenyl
  • SMILES CN1CCC(C2=CC=CC=C2)CC1

Description

Isonicotinic acid (IN) can be used as:An organocatalyst in the one pot four component condensation reaction, to synthesize pyranopyrazoles based heterocyclic compounds.An organic ligand for the preparation of copper(I) halide coordination polymer [CuBr(IN)]n, by hydrothermal method.As a starting material for the synthesis of cation-dimers with potent antimalarial activity.

Synthesis

  • Route1
    • null|null
      50-00-0
    • null|null
      771-99-3
    • ~71%
    • 1-Methyl-4-phenylpiperidine|CS-W001643
      774-52-7

    References

    • Rogers, Gary A.; Parsons, Stanley M.; Anderson, D. C.; Nilsson, Lena M.; Bahr, Ben A.; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1217 - 1230
  • Route2
    • 4-(4-Bromophenyl)-1-methyl-1,2,3,6-tetrahydropyridine|CS-0780504
      180912-08-7
    • ~90%
    • 1-Methyl-4-phenylpiperidine|CS-W001643
      774-52-7

    References

    • PROBIODRUG AG Patent: US2011/92501 A1, 2011 ; Location in patent: Page/Page column 132-133 ;
  • Route3

    References

    • Romanelli; Manetti; Scapecchi; Borea; Dei; Bartolini; Ghelardini; Gualtieri; Guandalini; Varani Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3946 - 3955

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   2.4958
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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