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Structure of 773134-84-2
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Ethyl 1-bromo-2-naphthoate features a brominated naphthalene core paired with an ester handle, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The electron-deficient aromatic ring enhances reactivity toward palladium-catalyzed transformations, while the ethyl ester group offers synthetic versatility for downstream derivatization. This bench-stable reagent integrates seamlessly into complex molecular architectures requiring halogen-directed assembly.
Ethyl 1-bromo-2-naphthoate serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established aryl bromide functionality. The ester group provides compatibility with standard functional group manipulations, while the naphthalene core offers rigidity and π-conjugation beneficial for advanced heterocycle synthesis. Its bench stability and ease of purification make it suitable for iterative coupling strategies and modular scaffold construction in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: