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Structure of 77168-85-5
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Methyl 5-chloro-6-methylpyrazine-2-carboxylate features a pyrazine core functionalized with chlorine, methyl, and ester groups, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient ring facilitates nucleophilic substitution, while the ester moiety offers versatility in downstream transformations. This bench-stable reagent streamlines access to complex nitrogen-rich architectures in medicinal chemistry and materials synthesis.
Methyl 5-chloro-6-methylpyrazine-2-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its pyrazine core supports diverse functionalization, with the chloro group enabling palladium-catalyzed cross-coupling reactions and the ester moiety permitting selective reduction or hydrolysis. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic workflows targeting bioactive scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: