3-Chlorobenzo[d]isothiazole

Name: 3-Chlorobenzo[d]isothiazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 7716-66-7
Cat. No. CS-W016032
Purity≥98%
MDL No.MFCD00673254

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 7716-66-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

3-Chlorobenzo[d]isothiazole is a heterocyclic scaffold featuring a chlorine substituent at the 3-position, offering enhanced electron-withdrawing character and improved metabolic stability. This moiety integrates readily into pharmaceutical intermediates and functional materials, providing a robust platform for C–H functionalization and transition metal-catalyzed coupling reactions under standard conditions.

Application

3-Chlorobenzo[d]isothiazole serves as a versatile building block for heterocyclic synthesis, enabling efficient construction of bioactive scaffolds through palladium-catalyzed cross-coupling reactions. Its electrophilic chlorine atom facilitates direct functionalization under mild conditions, while the fused isothiazole ring imparts structural rigidity and enhanced metabolic stability. The compound exhibits excellent bench stability and compatibility with diverse functional groups, making it ideal for iterative synthesis in medicinal chemistry and process development workflows.

General Information

CAS No. 7716-66-7
Cat. No. CS-W016032
Purity ≥98%
MDL No. MFCD00673254
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄ClNS
Molecular Weight 169.63
Synonym(s) 3-Chloro-1,2-benzisothiazole
SMILES ClC1=NSC2=CC=CC=C12

Computational Chemistry Data

TPSA 12.89
LogP 2.9497
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Benzoisothiazole compounds

Key Words

3-Chlorobenzo[d]isothiazole sigma3-Chlorobenzo[d]isothiazole manufacturer3-Chlorobenzo[d]isothiazole price3-Chlorobenzo[d]isothiazole structure3-Chlorobenzo[d]isothiazole SDSbuy 3-Chlorobenzo[d]isothiazole3-Chlorobenzo[d]isothiazole supplier3-Chlorobenzo[d]isothiazole uses3-Chlorobenzo[d]isothiazole molecular weightprice of 3-Chlorobenzo[d]isothiazole3-Chlorobenzo[d]isothiazole chemical name formula of 3-Chlorobenzo[d]isothiazole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Chlorobenzo[d]isothiazole

CAS No. 7716-66-7

Recommended Products