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CS-W001157 4
Total: USD 88.00

Fmoc-Tyr(Me)-OH

  • CAS No. 77128-72-4

  • Cat. No. CS-W011659
  • Purity≥98%
  • MDL No.MFCD00153368

*For research and further manufacturing use only, not for direct human use.

Fmoc-Tyr(Me)-OH|CS-W011659

Structure of 77128-72-4

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General Information

  • CAS No. 77128-72-4
  • Cat. No. CS-W011659
  • Purity ≥98%
  • MDL No. MFCD00153368
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₃NO₅
  • Molecular Weight 417.45
  • Synonym(s) None
  • SMILES O=C([C@@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)CC4=CC=C(OC)C=C4)O

Description

Fmoc-Tyr(Me)-OH is a protected tyrosine derivative featuring a methoxy substituent at the phenolic hydroxyl group. This modification enhances stability and modulates electronic properties, enabling efficient incorporation into peptide chains during solid-phase synthesis. The Fmoc group facilitates orthogonal deprotection, streamlining sequence assembly in complex peptide workflows.

Synthesis

  • Route1
    • null|null
      381222-43-1
    • ~62%
    • In-stock
      Fmoc-Tyr(Me)-OH|CS-W011659
      77128-72-4

    References

    • Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
  • Route2

    References

    • Synthesis, , # 3 p. 265 - 270
  • Route3

    References

    • Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   4.2296
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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