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CS-W001157 4
Total: USD 88.00

Pentafluorothiophenol

  • CAS No. 771-62-0

  • Cat. No. CS-0031672
  • Purity≥95%
  • MDL No.MFCD00004828

*For research and further manufacturing use only, not for direct human use.

Pentafluorothiophenol|CS-0031672

Structure of 771-62-0

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General Information

  • CAS No. 771-62-0
  • Cat. No. CS-0031672
  • Purity ≥95%
  • MDL No. MFCD00004828
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆HF₅S
  • Molecular Weight None
  • Synonym(s) 2,3,4,5,6-Pentafluorobenzenethiol
  • SMILES FC1=C(F)C(F)=C(F)C(S)=C1F

Description

Thalidomide-NH-C2-PEG3-OH is a PROTAC linker featuring a thalidomide, a hydrophilic PEG spacer, and an alcohol. Thalidomide is an E3 ligase activator, promoting the ubiquitinylation of a given protein. Meanwhile, the hydroxyl is a versatile group which may react in a number of ways.

Synthesis

  • Route1
    • null|null
      879-06-1
    • ~71%
    • In-stock
      Pentafluorothiophenol|CS-0031672
      771-62-0

    References

    • Bogoradovskii; Maksimov; Zubova Russian Journal of General Chemistry, 1999 , vol. 69, # 7 p. 1167 - 1172
  • Route2
    • null|null
      392-56-3
    • ~%
    • In-stock
      Pentafluorothiophenol|CS-0031672
      771-62-0

    References

    • Shtark, A. V.; Kizner, T. A.; Shteingarts, V. D. Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 2051 - 2056 Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 11 p. 2321 - 2327
  • Route3
    • null|null
      879-05-0
    • null|null
      7704-34-9
    • ~64%
    • In-stock
      Pentafluorothiophenol|CS-0031672
      771-62-0

    References

    • Brooke,G.M.; Quasem,M.A. Journal of the Chemical Society [Section] C: Organic, 1967 , p. 865 - 869 Full Text View citing articles Show Details Gmelin Handbook: F: PerFHalOrg.1, 1.1.6.2, page 97 - 116

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2920
Class : 8 (3)
Packing Group : Ⅱ
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.6708
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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