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CS-W001157 4
Total: USD 88.00

Ethyl 4-Boc-2-morpholinecarboxylate

  • CAS No. 768371-16-0

  • Cat. No. CS-W002813
  • Purity≥98%
  • MDL No.MFCD01646390

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-Boc-2-morpholinecarboxylate|CS-W002813

Structure of 768371-16-0

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General Information

  • CAS No. 768371-16-0
  • Cat. No. CS-W002813
  • Purity ≥98%
  • MDL No. MFCD01646390
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) Morpholine-2,4-dicarboxylic acid 4-tert-butyl ester 2-ethyl ester
  • SMILES CCOC(=O)C1OCCN(C1)C(=O)OC(C)(C)C

Description

Ethyl 4-Boc-2-morpholinecarboxylate features a protected morpholine ring enabling stable incorporation into complex molecular architectures. This bench-stable, moisture-tolerant building block facilitates efficient access to bioactive heterocycles through selective deprotection and functionalization under standard conditions.

Application

Ethyl 4-Boc-2-morpholinecarboxylate serves as a versatile morpholine-based building block for medicinal chemistry and peptide synthesis. The Boc-protected amine enables orthogonal functionalization, while the ester group facilitates subsequent transformations via hydrolysis or cross-coupling. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for modular assembly of complex heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1

    References

    • WO2004/74291 A1, ; Page 66-67 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   65.07
  • LogP   1.1854
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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