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CS-W001157 4
Total: USD 88.00

7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine

  • CAS No. 768350-54-5

  • Cat. No. CS-B1292
  • Molecule weight454.29
  • Purity≥98%
  • MDL No.MFCD19440903

*For research and further manufacturing use only, not for direct human use.

7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine|CS-B1292

Structure of 768350-54-5

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General Information

  • CAS No. 768350-54-5
  • Cat. No. CS-B1292
  • Purity ≥98%
  • MDL No. MFCD19440903
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₁₇BrFN₃O₂
  • Molecular Weight 454.29
  • Synonym(s) None
  • SMILES COC1=CC2=C(NC3=CC=C(Br)C=C3F)N=CN=C2C=C1OCC4=CC=CC=C4

Synthesis

  • Route1

    References

    • Gao, Mingzhang; Lola, Christian M.; Wang, Min; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3222 - 3226
  • Route2
    • 2-Amino-4-(benzyloxy)-5-methoxybenzamide|CS-0488230
      60547-98-0
    • ~%
    • 7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine|CS-B1292
      768350-54-5

    References

    • Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389
  • Route3

    References

    • Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   56.27
  • LogP   5.8626
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   6

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