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CS-W001157 4
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3-Iodo-2-isopropoxypyridine

  • CAS No. 766557-61-3

  • Cat. No. CS-0315602
  • Purity≥95%
  • MDL No.MFCD06659009

*For research and further manufacturing use only, not for direct human use.

3-Iodo-2-isopropoxypyridine|CS-0315602

Structure of 766557-61-3

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General Information

  • CAS No. 766557-61-3
  • Cat. No. CS-0315602
  • Purity ≥95%
  • MDL No. MFCD06659009
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀INO
  • Molecular Weight 263.08
  • Synonym(s) 2-Isopropoxy-3-iodo-pyridine
  • SMILES CC(C)OC1=C(C=CC=N1)I

Description

3-Iodo-2-isopropoxypyridine is a bench-stable, moisture-tolerant pyridine derivative featuring a strategically positioned iodine atom and an isopropoxy group. This combination enables efficient coupling reactions in cross-coupling protocols, particularly in the synthesis of functionalized heterocycles for medicinal chemistry applications.

Application

3-Iodo-2-isopropoxypyridine serves as a versatile building block for constructing biologically relevant pyridine-based scaffolds. The iodine atom enables reliable cross-coupling reactions, while the isopropoxy group provides steric and electronic modulation. This compound exhibits good bench stability and facilitates efficient functionalization in palladium-catalyzed transformations, making it well-suited for medicinal chemistry campaigns and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.4734
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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