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Structure of 766-99-4
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1-Ethynyl-4-iodobenzene serves as a key building block in transition-metal-catalyzed coupling reactions, featuring a terminal alkyne and iodide handle for efficient C–C and C–heteroatom bond formation. This bench-stable, moisture-tolerant aryl-iodide integrates seamlessly into Sonogashira and Suzuki-Miyaura protocols, enabling rapid access to conjugated biaryls and functionalized alkynes under standard conditions.
1-Ethynyl-4-iodobenzene serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, particularly in Sonogashira and Suzuki-Miyaura protocols. The terminal alkyne functionality enables efficient C–C bond formation, while the iodide group provides high reactivity in palladium-catalyzed coupling processes. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex aryl-alkynyl architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: