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Structure of 766-81-4
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3-Bromophenylacetylene is a bench-stable, moisture-tolerant alkyne reagent featuring a para-brominated aromatic ring that enables efficient copper-catalyzed coupling reactions. This electron-deficient acetylene integrates readily into complex molecular architectures, offering high functional group compatibility and predictable regioselectivity in Sonogashira and related transformations.
3-Bromophenylacetylene serves as a valuable building block in transition-metal-catalyzed coupling reactions, enabling efficient access to substituted biaryls and conjugated systems. Its bromine substituent provides high reactivity in palladium-catalyzed cross-couplings, while the terminal alkyne functionality supports Sonogashira and Glaser-type homocoupling protocols. The compound exhibits excellent bench stability and is compatible with a wide range of functional groups, facilitating straightforward purification and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS02,GHS07,GHS09
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H411
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Precautionary Statements : P210-P273-P280
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Lot numbers can be found on the outside label of a product: