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CS-W001157 4
Total: USD 88.00

4-Amino-1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one

  • CAS No. 76512-82-8

  • Cat. No. CS-0524260
  • Molecule weight529.58
  • Purity≥98%
  • MDL No.MFCD06796700

*For research and further manufacturing use only, not for direct human use.

4-Amino-1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one|CS-0524260

Structure of 76512-82-8

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General Information

  • CAS No. 76512-82-8
  • Cat. No. CS-0524260
  • Purity ≥98%
  • MDL No. MFCD06796700
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₃₁N₃O₆
  • Molecular Weight 529.58
  • Synonym(s) 5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
  • SMILES COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C(N=C(N)C=C5)=O)C[C@@H]4O

Synthesis

  • Route1
    • null|null
      117032-49-2
    • ~82%
    • 4-Amino-1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one|CS-0524260
      76512-82-8

    References

    • Isis Pharmaceuticals Inc. Patent: US2004/23382 A1, 2004 ; Location in patent: Page/Page column 17 ;
  • Route2

    References

    • Kataoka, Masanori; Hayakawa, Yoshihiro Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 6087 - 6089
  • Route3

    References

    • Hayakawa, Yoshihiro; Kataoka, Masanori Journal of the American Chemical Society, 1998 , vol. 120, # 48 p. 12395 - 12401

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H320
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362

Quality Control

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Computational Chemistry Data

  • TPSA   118.06
  • LogP   3.4998
  • H_Acceptors   9
  • H_Donors   2
  • Rotatable_Bonds   9

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