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3-mercapto-2-(mercaptomethyl)propanoic acid

  • CAS No. 7634-96-0

  • Cat. No. CS-M3522
  • Purity≥95%
  • MDL No.MFCD20638336

*For research and further manufacturing use only, not for direct human use.

3-mercapto-2-(mercaptomethyl)propanoic acid|CS-M3522

Structure of 7634-96-0

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General Information

  • CAS No. 7634-96-0
  • Cat. No. CS-M3522
  • Purity ≥95%
  • MDL No. MFCD20638336
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₂S₂
  • Molecular Weight 152.24
  • Synonym(s) Asparagusic acid, dihydro-; Dihydroasparagusic acid; β,β'-Dimercaptoisobutyric acid; 3-Sulfanyl-2-(sulfanylmethyl)propanoic acid
  • SMILES OC(C(CS)CS)=O

Description

This thiol-functional molecule features two reactive sulfhydryl groups in proximity, enabling efficient conjugation in bioconjugation and surface modification workflows. The carboxylic acid moiety provides additional anchoring capability for coupling to amine-containing substrates or biomolecules under standard conditions.

Application

3-Mercapto-2-(mercaptomethyl)propanoic acid serves as a versatile bifunctional thiol building block, enabling efficient conjugation and disulfide bridge formation in peptide synthesis and protein engineering. Its dual thiol functionality enhances reactivity in copper-catalyzed click chemistry and facilitates site-specific bioconjugation. The molecule exhibits good bench stability and simplifies purification due to its high polarity, making it well-suited for scalable applications in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2928
Class : 6.1,8
Packing Group : Ⅱ
Hazard Statements : H301-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.5468
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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