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Structure of 76272-35-0
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endo-8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine delivers a rigid, electron-rich scaffold ideal for medicinal chemistry optimization. This bench-stable, moisture-tolerant amine features a strategically positioned benzyl group that enhances lipophilicity and target engagement. The endo stereochemistry ensures precise spatial orientation for receptor binding, enabling efficient incorporation into bioactive molecules.
endo-8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine serves as a rigid, stereochemically defined scaffold for medicinal chemistry exploration. Its tertiary amine functionality enables facile salt formation and modulates solubility, while the bicyclic core provides conformational constraint ideal for probing receptor binding pockets. The benzyl group offers π-stacking potential and enhances metabolic stability. This compound reacts predictably in standard functionalization protocols, including reductive amination and alkylation, and exhibits bench stability under ambient conditions—ideal for high-throughput screening campaigns and analog synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: