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CS-W001157 4
Total: USD 88.00

3-Fluoro-2-methoxyphenylboronic acid

  • CAS No. 762287-59-2

  • Cat. No. CS-W020604
  • Purity≥97%
  • MDL No.MFCD03095355

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-2-methoxyphenylboronic acid|CS-W020604

Structure of 762287-59-2

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General Information

  • CAS No. 762287-59-2
  • Cat. No. CS-W020604
  • Purity ≥97%
  • MDL No. MFCD03095355
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BFO₃
  • Molecular Weight 169.95
  • Synonym(s) boronic acid, B-(3-fluoro-2-methoxyphenyl)-
  • SMILES COC1=C(F)C=CC=C1B(O)O

Description

3-Fluoro-2-methoxyphenylboronic acid features a boronate moiety appended to a fluorinated, methoxy-substituted aromatic ring, enabling efficient Suzuki-Miyaura coupling under standard conditions. The ortho-fluoro and meta-methoxy groups enhance reactivity while maintaining bench-stable handling characteristics.

Application

3-Fluoro-2-methoxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds. Its ortho-fluoro and methoxy substituents provide enhanced electronic modulation and metabolic stability, while the boronic acid group offers excellent bench stability and compatibility with diverse reaction conditions. Facilitates rapid access to substituted phenyl rings relevant in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.4859
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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