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CS-W001157 4
Total: USD 88.00

5-Amino-2-(4-aminophenyl)benzimidazole

  • CAS No. 7621-86-5

  • Cat. No. CS-0095841
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Amino-2-(4-aminophenyl)benzimidazole|CS-0095841

Structure of 7621-86-5

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General Information

  • CAS No. 7621-86-5
  • Cat. No. CS-0095841
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂N₄
  • Molecular Weight 224.26
  • Synonym(s) 5-Amino-2-(4-aminophenyl)-benzimidazole
  • SMILES NC1=CC=C(C2=NC3=CC(N)=CC=C3N2)C=C1

Description

5-Amino-2-(4-aminophenyl)benzimidazole features a dual amine-functionalized benzimidazole core that enables versatile conjugation and coordination in synthetic applications. This electron-rich scaffold integrates readily into functional materials and serves as a key building block for fluorescent probes and metal-chelating systems.

Application

5-Amino-2-(4-aminophenyl)benzimidazole serves as a versatile building block for heterocyclic synthesis, enabling the construction of biologically relevant scaffolds through standard coupling and cyclization protocols. Its dual amino functionalities offer enhanced reactivity in amide bond formation, Suzuki-Miyaura coupling, and electrophilic substitution reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for medicinal chemistry campaigns and process-scale applications.

Synthesis

  • Route1
    • Benzene-1,2,4-triaminedihydrochloride|CS-0171059
      615-47-4
    • 4-Aminobenzoic acid Conivaptan Impurity|CS-0213989
      150-13-0
    • ~%
    • In-stock
      5-Amino-2-(4-aminophenyl)benzimidazole|CS-0095841
      7621-86-5

    References

    • US2014/66629 A1, ; Paragraph 0084; 0085 ;
  • Route2
    • null|null
      97-02-9
    • ~%
    • In-stock
      5-Amino-2-(4-aminophenyl)benzimidazole|CS-0095841
      7621-86-5

    References

    • US2014/66629 A1, ;
  • Route3
    • null|null
      37632-91-0
    • ~%
    • In-stock
      5-Amino-2-(4-aminophenyl)benzimidazole|CS-0095841
      7621-86-5

    References

    • Chemische Berichte, , vol. 32, p. 2179

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H315-H319-H340
Precautionary Statements : P264-P280-P302+P352-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.72
  • LogP   2.3943
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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