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CS-W001157 4
Total: USD 88.00

3-Phenylazetidine hydrochloride

  • CAS No. 7606-30-6

  • Cat. No. CS-W018873
  • Molecule weight169.65
  • Purity≥96%
  • MDL No.MFCD08703190

*For research and further manufacturing use only, not for direct human use.

3-Phenylazetidine hydrochloride|CS-W018873

Structure of 7606-30-6

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General Information

  • CAS No. 7606-30-6
  • Cat. No. CS-W018873
  • Purity ≥96%
  • MDL No. MFCD08703190
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂ClN
  • Molecular Weight 169.65
  • Synonym(s) 3-Phenylazetidine HCl
  • SMILES [H]Cl.C1(C2=CC=CC=C2)CNC1

Description

3-Phenylazetidine hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a strained four-membered azetidine ring fused to a phenyl group. This configuration imparts enhanced reactivity and conformational rigidity, enabling efficient incorporation into bioactive molecules. The hydrochloride salt improves solubility and handling in aqueous reaction media.

Application

3-Phenylazetidine hydrochloride serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive heterocycles through established coupling and functionalization protocols. Its azetidine core provides enhanced metabolic stability and improved physicochemical properties in drug candidates. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis and scale-up applications in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.7952
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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