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CS-W001157 4
Total: USD 88.00

4-Boc-2-Oxopiperazine

  • CAS No. 76003-29-7

  • Cat. No. CS-W001639
  • Purity≥97%
  • MDL No.MFCD02181069

*For research and further manufacturing use only, not for direct human use.

4-Boc-2-Oxopiperazine|CS-W001639

Structure of 76003-29-7

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General Information

  • CAS No. 76003-29-7
  • Cat. No. CS-W001639
  • Purity ≥97%
  • MDL No. MFCD02181069
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆N₂O₃
  • Molecular Weight 200.23
  • Synonym(s) None
  • SMILES O=C1NCCN(C(OC(C)(C)C)=O)C1

Description

4-Boc-2-Oxopiperazine features a protected piperazinone core with a tert-butoxycarbonyl group at the 4-position, enabling stable incorporation into peptide and heterocyclic syntheses. This bench-stable derivative facilitates efficient access to functionalized piperazine scaffolds under standard conditions.

Synthesis

  • Route1

    References

    • GLAXOSMITHKLINE LLC; BANKA, Anna; CATALANO, John, G.; CHONG, Pek, Yoke; FANG, Jing; GARRIDO, Dulce, Maria; PEAT, Andrew, James; PRICE, Daniel, J.; SHOTWELL, John, Brad; TAI, Vincent; ZHANG, Huichang Patent: WO2011/41713 A2, 2011 ; Location in patent: Page/Page column 147-148 ;
  • Route2
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • null|null
      105-39-5
    • ~33%
    • In-stock
      4-Boc-2-Oxopiperazine|CS-W001639
      76003-29-7

    References

    • Merck Sharp and Dohme Ltd. Patent: US5998415 A1, 1999 ; US 5998415 A
  • Route3

    References

    • ELAN PHARMACEUTICALS INC; PHARMACIA & UPJOHN COMPANY Patent: JP2005/504737 A, 2005 ; Location in patent: Page/Page column 129-130 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.64
  • LogP   0.3533
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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