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CS-W001157 4
Total: USD 88.00

N-Lauroylglycine

  • CAS No. 7596-88-5

  • Cat. No. CS-0201674
  • Purity≥98%
  • MDL No.MFCD00153470

*For research and further manufacturing use only, not for direct human use.

N-Lauroylglycine|CS-0201674

Structure of 7596-88-5

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General Information

  • CAS No. 7596-88-5
  • Cat. No. CS-0201674
  • Purity ≥98%
  • MDL No. MFCD00153470
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇NO₃
  • Molecular Weight 257.37
  • Synonym(s) N-Dodecanoyl-glycine
  • SMILES CCCCCCCCCCCC(NCC(O)=O)=O

Description

N-Lauroylglycine delivers a long-chain aliphatic acyl group linked to a glycine backbone, enabling efficient conjugation in peptide synthesis. This amphiphilic structure enhances solubility and stability under standard conditions, facilitating use in bioconjugation and membrane protein studies.

Application

N-Lauroylglycine serves as a versatile amphiphilic building block, enabling efficient synthesis of peptide conjugates and surfactant systems. Its lauroyl chain provides hydrophobic character for membrane interaction studies, while the glycine moiety offers a reactive amine for site-specific derivatization. The compound exhibits excellent bench stability, facilitates straightforward purification via crystallization or chromatography, and demonstrates broad compatibility in aqueous and organic media.

Synthesis

  • Route1

    References

    • Conopco, Inc., d/b/a UNILEVER Patent: US2007/299269 A1, 2007 ; Location in patent: Page/Page column 5; 6 ;
  • Route2
    • null|null
      112-16-3
    • Glycine, 99%|CS-1269057
      56-40-6
    • ~88%
    • In-stock
      N-Lauroylglycine|CS-0201674
      7596-88-5

    References

    • Kusama; Soga; Ono; Kumazawa; Shioya; Nakayama; Uoto; Osada Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 12 p. 3244 - 3253
  • Route3

    References

    • Vavrova, Katerina; Hrabalek, Alexandr; Dolezal, Pavel; Samalova, Lucie; Palat, Karel; Zbytovska, Jarmila; Holas, Tomas; Klimentova, Jana Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 24 p. 5381 - 5390

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   3.1081
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   12

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