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CS-W001157 4
Total: USD 88.00

3-Fluoro-5-iodopyridine

  • CAS No. 757950-13-3

  • Cat. No. CS-0042002
  • Purity≥97%
  • MDL No.MFCD08457780

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-5-iodopyridine|CS-0042002

Structure of 757950-13-3

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General Information

  • CAS No. 757950-13-3
  • Cat. No. CS-0042002
  • Purity ≥97%
  • MDL No. MFCD08457780
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃FIN
  • Molecular Weight 222.99
  • Synonym(s) 5-Fluoro-3-iodopyridine
  • SMILES FC1=CC(I)=CN=C1

Application

3-Fluoro-5-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. Its orthogonal reactivity profile—where the fluorine facilitates nucleophilic substitution while the iodine supports palladium-catalyzed coupling—enables sequential functionalization. The compound exhibits excellent bench stability and is compatible with standard reaction conditions, facilitating straightforward purification and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   1.8253
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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