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Structure of 75711-00-1
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2-Chloro-3-methoxy-5-nitropyridine features a strategically positioned nitro group that enhances electrophilic reactivity, while the methoxy substituent improves solubility and stability. This electron-deficient pyridine scaffold enables efficient coupling in transition-metal-catalyzed reactions, serving as a key intermediate in the synthesis of functionalized heterocycles for pharmaceutical and agrochemical applications.
2-Chloro-3-methoxy-5-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling efficient functionalization at the 2-position via palladium-catalyzed cross-coupling. The chloro group exhibits high reactivity in Suzuki, Stille, and Negishi reactions, while the methoxy and nitro substituents provide orthogonal handles for further modification. Bench-stable and compatible with standard purification methods, it facilitates the construction of complex pyridine-based scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: