Fludarabine phosphate

Name: Fludarabine phosphate
Brand: ChemScene
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CAS No. 75607-67-9
Cat. No. CS-0861
Purity≥98%
MDL No.MFCD00866418

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

Polynucleotide involved in protein synthesis. Found in both the nucleus and the cytoplasm of cells.

Application

Fludarabine (phosphate) serves as a prodrug precursor enabling intracellular delivery of fludarabine, a purine nucleoside analog with established utility in purine metabolism inhibition. Its phosphate ester functionality facilitates enzymatic activation to the active 5'-monophosphate form, supporting consistent incorporation into DNA during replication. The compound exhibits bench stability and compatibility with standard nucleoside synthesis workflows, facilitating use in the construction of antimetabolite scaffolds for oncology research.

General Information

CAS No. 75607-67-9
Cat. No. CS-0861
Purity ≥98%
MDL No. MFCD00866418
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃FN₅O₇P
Molecular Weight 365.21
Synonym(s) NSC 118218 (phosphate)
SMILES NC1=C2C(N([C@H]3[C@@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O3)C=N2)=NC(F)=N1

Computational Chemistry Data

TPSA 186.07
LogP -1.7239
H_Acceptors 10
H_Donors 5
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS08
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H341-H361
Precautionary Statements : P280-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Purine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Nucleosides & Nucleotides Ribonucleotide

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleotide Analogs

Biochemistry Biochemicals and Reagents Pharmaceutical Research Reagents Antitumor Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Pharmaceutical Research Reagents Antitumor Research Reagents

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Fludarabine phosphate

CAS No. 75607-67-9

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