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Structure of 755027-21-5
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4-Chloro-1-iodo-2-methoxybenzene features a strategically positioned iodine atom enabling efficient palladium-catalyzed cross-coupling reactions. The ortho-methoxy group enhances solubility and stabilizes reaction intermediates, while the chloro substituent offers orthogonal reactivity. This dual-functional aryl halide integrates readily into complex molecular architectures under standard conditions.
4-Chloro-1-iodo-2-methoxybenzene serves as a versatile diaryl building block in cross-coupling chemistry, enabling palladium-catalyzed reactions such as Suzuki-Miyaura and Stille couplings. The ortho-iodo and para-chloro groups provide complementary reactivity for sequential functionalization, while the methoxy group enhances solubility and modulates electronic properties. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of complex aryl scaffolds relevant to pharmaceutical and agrochemical development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: