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CS-W001157 4
Total: USD 88.00

4-Phenylthiazole-2-carbaldehyde

  • CAS No. 75390-44-2

  • Cat. No. CS-0156391
  • Purity≥95%
  • MDL No.MFCD02665589

*For research and further manufacturing use only, not for direct human use.

4-Phenylthiazole-2-carbaldehyde|CS-0156391

Structure of 75390-44-2

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General Information

  • CAS No. 75390-44-2
  • Cat. No. CS-0156391
  • Purity ≥95%
  • MDL No. MFCD02665589
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NOS
  • Molecular Weight 189.23
  • Synonym(s) 4-PHENYL-THIAZOLE-2-CARBALDEHYDE
  • SMILES C1=CC=C(C=C1)C2=CSC(=N2)C=O

Description

4-Phenylthiazole-2-carbaldehyde features a conjugated thiazole-aldehyde system that enables direct integration into heterocyclic scaffolds. The phenyl group enhances planarity and electron delocalization, while the aldehyde moiety provides a reactive handle for nucleophilic additions. This compound serves as a key building block in the synthesis of bioactive molecules and functional materials.

Application

4-Phenylthiazole-2-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds prevalent in medicinal chemistry. Its aldehyde functionality facilitates nucleophilic additions, condensations, and coupling reactions under mild conditions. The molecule exhibits good bench stability and is readily purified by chromatography or recrystallization, making it suitable for high-throughput screening and process-scale applications.

Synthesis

  • Route1
    • (4-Phenyl-1,3-thiazol-2-yl)methanol|CS-0248754
      65384-99-8
    • ~%
    • In-stock
      4-Phenylthiazole-2-carbaldehyde|CS-0156391
      75390-44-2

    References

    • Journal of the American Chemical Society, , vol. 53, p. 1470,1472 Anales de la Real Sociedad Espanola de Fisica y Quimica, , vol. <B> 50, p. 609,614
  • Route2
    • null|null
      70-11-1
    • ~%
    • In-stock
      4-Phenylthiazole-2-carbaldehyde|CS-0156391
      75390-44-2

    References

    • Journal of the American Chemical Society, , vol. 53, p. 1470,1472
  • Route3
    • null|null
      858009-07-1
    • ~%
    • In-stock
      4-Phenylthiazole-2-carbaldehyde|CS-0156391
      75390-44-2

    References

    • Journal of the American Chemical Society, , vol. 53, p. 1470,1472

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.6226
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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