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CS-W001157 4
Total: USD 88.00

tert-Butyl 2,6-dichloroisonicotinate

  • CAS No. 75308-46-2

  • Cat. No. CS-0098675
  • Purity≥98%
  • MDL No.MFCD08445655

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,6-dichloroisonicotinate|CS-0098675

Structure of 75308-46-2

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General Information

  • CAS No. 75308-46-2
  • Cat. No. CS-0098675
  • Purity ≥98%
  • MDL No. MFCD08445655
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁Cl₂NO₂
  • Molecular Weight 248.11
  • Synonym(s) tert-Butyl 2,6-Dichloro-4-pyridinecarboxylate
  • SMILES O=C(C1=CC(Cl)=NC(Cl)=C1)OC(C)(C)C

Synthesis

  • Route1

    References

    • McDermott, Todd S.; Bhagavatula, Lakshmi; Borchardt, Thomas B.; Engstrom, Kenneth M.; Gandarilla, Jorge; Kotecki, Brian J.; Kruger, Albert W.; Rozema, Michael J.; Sheikh, Ahmad Y.; Wagaw, Seble H.; Wittenberger, Steven J. Organic Process Research and Development, 2009 , vol. 13, # 6 p. 1145 - 1155
  • Route2

    References

    • Schmidt, Gunther; Reber, Stefan; Bolli, Martin H.; Abele, Stefan Organic Process Research and Development, 2012 , vol. 16, # 4 p. 595 - 604
  • Route3
    • In-stock
      2,6-Dichloroisonicotinic acid|CS-W007536
      5398-44-7
    • null|null
      115-11-7
    • ~40%
    • In-stock
      tert-Butyl 2,6-dichloroisonicotinate|CS-0098675
      75308-46-2

    References

    • ELI LILLY AND COMPANY Patent: WO2005/108358 A2, 2005 ; Location in patent: Page/Page column 76 ; WO 2005/108358 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   3.3437
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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