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CS-W001157 4
Total: USD 88.00

22-Methoxy-22-oxodocosanoic acid

  • CAS No. 7511-30-0

  • Cat. No. CS-0527943
  • Molecule weight384.60
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

22-Methoxy-22-oxodocosanoic acid|CS-0527943

Structure of 7511-30-0

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General Information

  • CAS No. 7511-30-0
  • Cat. No. CS-0527943
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₄₄O₄
  • Molecular Weight 384.60
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCCCCCCCCCCCCCCCC(=O)OC

Description

22-Methoxy-22-oxodocosanoic acid features a terminal carboxylic acid group flanked by a methoxy and oxo substituent at the C22 position, enabling precise functionalization in lipid-based synthetic pathways. This sterically defined, bench-stable derivative supports tailored conjugation strategies in bioconjugate chemistry and materials science applications.

Application

22-Methoxy-22-oxodocosanoic acid serves as a versatile β-keto ester surrogate, enabling efficient aldol and Michael additions under mild conditions. Its terminal aliphatic chain and orthogonal functional groups facilitate downstream modifications in complex molecule synthesis. The methoxy carbonyl moiety enhances stability and simplifies purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and natural product derivatization.

Synthesis

  • Route1
    • Dimethyl docosanedioate|CS-1171235
      22399-98-0
    • ~%
    • In-stock
      22-Methoxy-22-oxodocosanoic acid|CS-0527943
      7511-30-0

    References

    • Hnevsova et al. Collection of Czechoslovak Chemical Communications, 1956 , vol. 21, p. 1459,1465 Show Details Chicoisne et al. Bulletin de la Societe Chimique de France, 1957 , p. 1232,1236 Show Details Jensen Finnish Paper Timber J., 1950 , vol. 32, p. 293
  • Route2

    References

    • Drake; Carhart; Mozingo Journal of the American Chemical Society, 1941 , vol. 63, p. 619
  • Route3

    References

    • Buller; Cohen, Hagai; Jensen; Kjaer; Lahav; Leiserowitz Journal of Physical Chemistry B, 2001 , vol. 105, # 46 p. 11447 - 11455

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   7.046
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   21

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